Description

N,n-Dimethyl-13C2-Formamide is a stable isotope-labeled analog of the common polar aprotic solvent, N,N-Dimethylformamide (DMF). This compound, with two carbon-13 atoms incorporated into its molecular structure, is an essential tool for advanced analytical and research applications where isotopic tracing is required. It is primarily utilized by researchers and scientists in pharmaceutical development, metabolic studies, and NMR spectroscopy to gain detailed mechanistic insights and improve analytical sensitivity.

Application

• NMR Spectroscopy & Analytical Standards: Serves as a critical internal standard or solvent for quantitative nuclear magnetic resonance (qNMR) and other spectroscopic techniques, enabling precise quantification and structural elucidation.
• Pharmaceutical Research & Development: Used as a labeled reagent or solvent in the synthesis and metabolic pathway tracing of active pharmaceutical ingredients (APIs) and drug candidates.
• Metabolic Studies & Biomarker Research: Acts as a tracer in mass spectrometry-based metabolomics and proteomics to study biochemical pathways, drug metabolism, and disease mechanisms.
• Chemical Synthesis & Process Chemistry: Employed as a labeled solvent or reactant in organic synthesis, particularly for reactions requiring DMF, to track atom incorporation and reaction mechanisms.
• Environmental & Geochemical Tracing: Applied in specialized environmental fate studies to track the movement and transformation of chemical compounds.

Basic Information

Product Name	N,n-Dimethyl-13C2-Formamide
CAS No.	117880-10-1
Molecular Formula	C13H7NO
Molecular Weight	75.07 g/mol (for 13C2 isotopologue)
Synonyms	N,N-Dimethyl-13C2-formamide; DMF-13C2; [13C2]-N,N-Dimethylformamide; (N,N-Dimethylformamide)-13C2; N,N-Dimethylformamide-13C2; Formamide, N,N-dimethyl-13C2-; Stable Isotope Labeled DMF; 13C Labeled DMF
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-13C2-Formamide is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized using advanced analytical techniques including NMR, GC-MS, and HPLC to verify isotopic enrichment, chemical purity, and identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (atom % 13C), chemical assay, and solvent residue profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99% (or as specified)
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.