Description

1-Ethynylcyclobutanol is a versatile and highly reactive organic building block featuring both an alkyne and a hydroxyl group on a strained cyclobutane ring. This unique molecular architecture makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical R&D teams for constructing novel scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can impart unique biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, ring-opening polymerizations, and the synthesis of complex natural product analogs.
• Ligand and Catalyst Development: Useful for creating novel ligands in coordination chemistry and catalysis due to its functional group diversity.

Basic Information

Product Name	1-Ethynylcyclobutanol
CAS No.	98135-75-2
Molecular Formula	C6H8O
Molecular Weight	96.13 g/mol
Synonyms	1-Ethynylcyclobutanol; Cyclobutanol, 1-ethynyl-; 1-Ethynyl-1-cyclobutanol; Ethynylcyclobutanol
EINECS	Contact for details

Quality Control

Our 1-Ethynylcyclobutanol is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.