Description

Brevetoxin Pbtx-1 is a potent marine neurotoxin belonging to the class of polycyclic ether compounds, primarily produced by the dinoflagellate *Karenia brevis*. This high-purity reference standard is critical for analytical research, toxicological studies, and the development of detection methods for harmful algal blooms. It is an essential material for researchers and laboratories in environmental monitoring, marine biology, and public health sectors requiring precise analytical standards.

Application

• Analytical Reference Standard: Primary use as a certified standard for the calibration and validation of analytical methods (e.g., LC-MS, HPLC) to detect and quantify brevetoxins in environmental and biological samples.
• Toxicological Research: Fundamental tool for studying the mechanism of action, dose-response relationships, and cellular effects of brevetoxin exposure in in vitro and in vivo models.
• Environmental Monitoring & HAB Studies: Used to assess and monitor the toxicity levels during harmful algal bloom (HAB) events in coastal waters and shellfish.
• Diagnostic Development: Key component in the research and development of immunoassays, biosensors, and other rapid detection kits for shellfish poisoning.
• Pharmacological Studies: Investigated for its specific interaction with voltage-gated sodium channels, serving as a probe in neurophysiology and pharmacology research.
• Quality Control & Assurance: Employed by regulatory bodies and testing laboratories to ensure the accuracy and reliability of brevetoxin testing in food safety (shellfish) and water quality programs.

Basic Information

Item	Detail
Product Name	Brevetoxin Pbtx-1
CAS No.	98112-41-5
Molecular Formula	C50H70O14
Molecular Weight	895.1 g/mol
Synonyms	Brevetoxin-1; PbTx-1; GB-1; *Karenia brevis* Toxin 1; BTX-B1; Polyether brevetoxin B; 3,4-Epoxy-14,15-dihydro-47-deoxybrevetoxin B
EINECS	Contact for details

Quality Control

Every batch of Brevetoxin Pbtx-1 is produced and analyzed under strict quality protocols to ensure identity, purity, and stability. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity reference materials. Certificates of Analysis (COA) providing detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time matches reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in methanol, acetonitrile, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.