Description

Atriopeptin Ii CAS NO 98084-69-6 is a synthetic peptide fragment corresponding to the atrial natriuretic peptide (ANP) system, a key regulator of blood pressure and fluid-electrolyte balance. This compound serves as a critical research tool for investigating cardiovascular physiology, renal function, and hormone-receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on cardiovascular drug discovery and metabolic studies.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of the atrial natriuretic peptide (ANP) pathway and its physiological effects.
• Cardiovascular Pharmacology: Investigation of mechanisms for blood pressure regulation, vasodilation, and natriuresis (sodium excretion).
• Receptor Binding Assays: Essential for competitive binding studies to characterize and quantify ANP receptor subtypes (NPR-A, NPR-C).
• Enzyme Activity Studies: Employed in research on neutral endopeptidase (NEP) activity and peptide hormone metabolism.
• In Vitro & In Vivo Models: Administration in cell-based assays and animal models to study heart failure, hypertension, and renal diseases.
• Diagnostic Development: Potential use in the development of immunoassays for detecting ANP-related biomarkers.

Basic Information

Product Name	Atriopeptin Ii
CAS No.	98084-69-6
Molecular Formula	C106H166N34O31S2
Molecular Weight	2432.8 g/mol
Synonyms	Atrial Natriuretic Peptide (7-23); ANP (7-23); Atriopeptin 23; Cardionatrin I (7-23); hANP (7-23); Atriopeptin II; Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Our Atriopeptin Ii is produced under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.