Description

1H-Pyrazole-4-Carbonitrile, 3-Amino-1-(2-Hydroxyethyl)- is a versatile pyrazole derivative featuring both amino and nitrile functional groups on the heterocyclic core. This compound is a critical pharmaceutical intermediate and building block for the synthesis of more complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Chelating Agent: The amino and nitrile groups make it a useful starting material for creating ligands in coordination chemistry and catalysis.
• Heterocyclic Chemistry Research: Fundamental building block for constructing more complex pyrazole, pyrazolo[3,4-d]pyrimidine, and fused heterocyclic systems in medicinal chemistry.
• Dye and Pigment Intermediate: Used in the development of specialized colorants and functional dyes.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.

Basic Information

Product Name	1H-Pyrazole-4-Carbonitrile, 3-Amino-1-(2-Hydroxyethyl)-
CAS No.	98035-87-1
Molecular Formula	C6H8N4O
Molecular Weight	152.16 g/mol
Synonyms	3-Amino-1-(2-hydroxyethyl)-1H-pyrazole-4-carbonitrile; 1-(2-Hydroxyethyl)-3-amino-1H-pyrazole-4-carbonitrile; 3-Amino-1-(2-hydroxyethyl)pyrazole-4-carbonitrile; 4-Cyano-3-amino-1-(2-hydroxyethyl)pyrazole; 98035-87-1; 1H-Pyrazole-4-carbonitrile, 3-amino-1-(2-hydroxyethyl)-; 3-Amino-1-(β-hydroxyethyl)pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Carbonitrile, 3-Amino-1-(2-Hydroxyethyl)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent quality suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.