Description

Angiogenin CAS NO 97950-81-7 is a potent, 14.1 kDa protein that plays a critical role in stimulating the formation of new blood vessels, a process known as angiogenesis. This biological activity makes it an essential research tool for studying vascular biology, tumor growth, and tissue regeneration. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from basic research to therapeutic development.

Application

• Biomedical Research: Fundamental studies on the mechanisms of angiogenesis, vasculogenesis, and endothelial cell biology.
• Cancer Research: Investigation of tumor angiogenesis, metastasis, and the development of anti-angiogenic therapies.
• Therapeutic Development: Serves as a reference standard or active component in the development of pro- or anti-angiogenic drugs and biologics.
• Wound Healing & Regenerative Medicine: Research into enhancing tissue repair, ischemic disease treatment, and engineered tissue vascularization.
• Diagnostic Assay Development: Used as a calibrant or target protein in ELISA, immunoassays, and other bioanalytical methods.
• Cell Culture & In Vitro Models: Supplement for inducing angiogenesis in 3D cell cultures, organoids, and other advanced research models.

Basic Information

Product Name	Angiogenin
CAS No.	97950-81-7
Molecular Formula	C644H1003N173O193S9
Molecular Weight	~14.4 kDa
Synonyms	Angiogenin; Ribonuclease 5; RNASE5; Human Angiogenin; ANG; HsRNAse; EC 3.1.27.-; Angiogenesis Factor
EINECS	Contact for details

Quality Control

Our Angiogenin is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Specifications typically include assessment by SDS-PAGE, HPLC, mass spectrometry, and endotoxin testing. A Certificate of Analysis (COA) detailing purity, potency, and specific test results is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band at ~14 kDa
Purity (HPLC)	≥ 95%
Biological Activity	Confirmed by endothelial cell proliferation/tube formation assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.