Description

1'-[3-[[10,11-Dihydro-5H-Dibenz[B,F]Azepin]-5-Yl]Propyl]-1,5,6,7,8,8A-Hexahydrospiro[Imidazo[1,2-A]Pyridine-3,4'-Piperidin]-2-One is a complex, high-purity pharmaceutical intermediate with a unique spirocyclic and tricyclic fused ring structure. This compound is of significant value for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in the central nervous system (CNS) therapeutic area. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel neuropsychiatric and neurological drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel psychotropic and neuroactive drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents targeting CNS disorders.
• API Synthesis: A key raw material in the production of complex molecules for potential treatments of conditions like depression, anxiety, or schizophrenia.
• Biochemical Research: Employed as a reference standard or ligand in pharmacological assays to study receptor binding and enzyme inhibition.
• Process Chemistry: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Acts as a starting point for the custom manufacturing of specialized analogs and derivatives for client-specific research programs.

Basic Information

Product Name	1'-[3-[[10,11-Dihydro-5H-Dibenz[B,F]Azepin]-5-Yl]Propyl]-1,5,6,7,8,8A-Hexahydrospiro[Imidazo[1,2-A]Pyridine-3,4'-Piperidin]-2-One
CAS No.	97716-05-7
Molecular Formula	C31H38N4O
Molecular Weight	482.66 g/mol
Synonyms	1'-[3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]-1,5,6,7,8,8a-hexahydrospiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one; Spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one, 1'-[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]-1,5,6,7,8,8a-hexahydro-; UNII-9V2I6V8J4S; 9V2I6V8J4S; 1'-[3-(5H-Dibenzo[b,f]azepin-5-yl)propyl]octahydrospiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one (non-specific); CAS 97716-05-7.
EINECS	Contact for details

Quality Control

Our 1'-[3-[[10,11-Dihydro-5H-Dibenz[B,F]Azepin]-5-Yl]Propyl]-1,5,6,7,8,8A-Hexahydrospiro[Imidazo[1,2-A]Pyridine-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.