Description

Neurokinin B (4-10) is a specific bioactive fragment of the full neurokinin B peptide, identified by CAS NO 97559-39-2. This compound is a valuable research tool for studying the neurokinin receptor system, particularly the NK3 receptor subtype, due to its selective biological activity. It is primarily needed by researchers and developers in the fields of neuroscience, pharmacology, and drug discovery for investigating neurological pathways and developing potential therapeutic agents.

Application

• Neuroscientific Research: Used as a selective agonist to study the function and distribution of NK3 receptors in the central and peripheral nervous systems.
• Pharmacological Assays: Employed in in vitro and in vivo assays to screen for NK3 receptor antagonists and modulators.
• Drug Discovery & Development: Serves as a reference standard and tool compound in preclinical research for conditions related to neurokinin signaling, such as psychiatric disorders, pain, and inflammation.
• Biochemical Studies: Utilized to investigate intracellular signaling cascades and downstream effects activated by NK3 receptor engagement.
• Academic & Institutional Research: A key reagent for universities and research institutes focusing on neuropeptide biology and receptor pharmacology.

Basic Information

Product Name	Neurokinin B (4-10)
CAS No.	97559-39-2
Molecular Formula	C38H58N12O9S
Molecular Weight	858.99 g/mol
Synonyms	Neurokinin B fragment 4-10; NKB (4-10); Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 (4-10 fragment); Tachykinin 3 (76-86) (human); NK3 Receptor Agonist (4-10); H-Asp-Met-His-Asp-Phe-Phe-Val-NH2; [Met(O2)10]-Neurokinin B (4-10) (oxidized form reference)
EINECS	Contact for details

Quality Control

Our Neurokinin B (4-10) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.