Description

Boc-Trp-N(Och3)Ch3 is a protected amino acid derivative, specifically a methoxy-modified tryptophan analog with a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical building block in advanced peptide synthesis, offering precise control over molecular structure and reactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes. Its unique modification provides enhanced stability and specific functional handles for complex conjugation strategies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of modified tryptophan residues into peptide chains.
• Medicinal Chemistry Research: Used in the design and synthesis of peptide-based drug candidates, enzyme inhibitors, and receptor ligands.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Chemical Biology Studies: Employed to probe protein-protein interactions and enzyme mechanisms using synthetically modified peptides.
• Process Development: Used in scaling up the production of specialized peptides for preclinical and clinical studies.

Basic Information

Product Name	Boc-Trp-N(Och3)Ch3
CAS No.	97530-05-7
Molecular Formula	C₂₀H₂₈N₂O₅
Molecular Weight	376.45 g/mol
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-N-methoxy-L-tryptophan methyl ester; Boc-N(OMe)-Trp-OMe; Boc-Tryptophan(OMe)-OMe; tert-Butyl N-methoxy-N-[(2S)-3-(1H-indol-3-yl)-1-methoxy-1-oxopropan-2-yl]carbamate; Methyl N-(tert-butoxycarbonyl)-N-methoxy-L-tryptophanate; Boc-L-Trp(OMe)-OMe; N-Boc-N-methoxy-L-tryptophan methyl ester
EINECS	Contact for details

Quality Control

Our Boc-Trp-N(Och3)Ch3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.