Description

Chymase CAS NO 97501-92-3 is a serine protease enzyme belonging to the chymotrypsin family, known for its role in the processing and degradation of various peptide substrates. This enzyme is of significant interest in biochemical research and pharmaceutical development due to its involvement in inflammatory and fibrotic pathways. It is primarily utilized by research institutions and biotechnology companies focused on cardiovascular disease, asthma, and tissue remodeling studies.

Application

• Biochemical Research: Used as a key reagent for studying protease activity, enzyme kinetics, and substrate specificity in vitro.
• Pharmaceutical R&D: Employed in drug discovery programs targeting chymase inhibitors for conditions like heart failure, atherosclerosis, and pulmonary fibrosis.
• Diagnostic Development: Serves as a component in assay kits for detecting and quantifying chymase activity in biological samples.
• Cell Biology Studies: Applied in research models to investigate the role of chymase in mast cell function, angiogenesis, and extracellular matrix remodeling.
• Peptide Chemistry: Utilized for the specific cleavage of peptide bonds in synthetic peptide analysis and protein sequencing.

Basic Information

Product Name	Chymase
CAS No.	97501-92-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mast Cell Protease I; α-Chymase; Chymotrypsin-like protease; Chymase 1; CMA1; Mast Cell Chymase; Chymotrypsin-like enzyme; EC 3.4.21.39
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized for activity, purity, and stability. Certificates of Analysis (COA) detailing specific parameters such as enzymatic activity (units/mg), purity level (by SDS-PAGE or HPLC), and endotoxin levels are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, aliquoting is recommended to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Assay (Enzymatic Activity)	≥ 95% of labeled activity
Purity (SDS-PAGE)	≥ 90%
Protein Content	By UV absorbance
Endotoxin	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.