Description

Cephapirin Benzathine CAS NO 97468-37-6 is a benzathine salt form of the first-generation cephalosporin antibiotic, cephapirin. This formulation is primarily valued for its enhanced stability and suitability for specific pharmaceutical manufacturing processes. It is a critical active pharmaceutical ingredient (API) and intermediate for producers of veterinary and human injectable antibiotic formulations.

Application

• Veterinary Pharmaceutical Manufacturing: Primary use as an active ingredient in intramammary infusions for the treatment of bovine mastitis in dairy cattle.
• Human Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of certain β-lactam antibiotic formulations.
• Bulk API Production: Supplied to contract manufacturing organizations (CMOs) and large-scale pharmaceutical companies for the production of sterile injectable dosage forms.
• Research & Development: Used in microbiological and pharmacological research to study the efficacy and stability of cephalosporin salts.
• Reference Standard: Suitable for use as a chemical reference standard in quality control laboratories when certified.

Basic Information

Product Name	Cephapirin Benzathine
CAS No.	97468-37-6
Molecular Formula	C34H50N8O10S2
Molecular Weight	794.95 g/mol
Synonyms	Cephapirin Benzathine Salt; Benzathine Cephapirin; (6R,7R)-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-7-[(2-thiophene-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid compound with N,N'-dibenzylethylenediamine; Cefapirin Benzathine; BL-P 1322 Benzathine; Cephapirin DBED Salt; Cefa-Lak (veterinary product component); Antibiotic BL-P 1322 Benzathine
EINECS	Contact for details

Quality Control

Our Cephapirin Benzathine is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, related substances, residual solvents, and microbiological quality. We can support compliance with cGMP, USP, and EP monograph requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be kept sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	+55° to +65° (c=1 in water)
pH (1% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.