Description

Na, Ne-Bis-Boc-L-2-Aminoadipamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is a critical building block for researchers and manufacturers developing complex peptides and peptidomimetics, offering superior control over reaction pathways. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers focused on creating novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key protected intermediate in the solid-phase and solution-phase synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Research & Development: Enables the controlled incorporation of the L-2-aminoadipic acid moiety into novel peptide sequences for structure-activity relationship (SAR) studies.
• Bioconjugation Chemistry: Serves as a precursor for creating specialized linkers and modified amino acids used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Protecting Group Strategy: The dual Boc-protection provides orthogonal deprotection options, facilitating complex multi-step synthetic routes in medicinal chemistry.
• Fine Chemical Synthesis: Used in the production of custom amino acid derivatives and non-natural amino acids for various high-value chemical applications.

Basic Information

Product Name	Na, Ne-Bis-Boc-L-2-Aminoadipamic Acid tert-Butyl Ester
CAS No.	97347-40-5
Molecular Formula	C₂₀H₃₆N₂O₈
Molecular Weight	432.51 g/mol
Synonyms	Boc-Aad(OtBu)-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]-5-[(tert-butoxycarbonyl)(tert-butoxy)amino]-5-oxopentanoic acid; L-2-Aminoadipic acid 6-(N-Boc)-N-Boc, 1-tert-butyl ester; Di-Boc-L-2-aminoadipic acid tert-butyl ester; tert-Butyl (2S)-2-[(tert-butoxycarbonyl)amino]-5-[(tert-butoxycarbonyl)(tert-butoxy)amino]-5-oxopentanoate; Nα,Nε-Bis-Boc-L-2-aminoadipamic acid tert-butyl ester; Boc-Aad(OtBu)-OH (protected form); 2-Aminoadipic acid derivative, Boc-protected
EINECS	Contact for details

Quality Control

Our Na, Ne-Bis-Boc-L-2-Aminoadipamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.