Description

Ethyl 3-(2,6-Difluorophenyl)-3-Oxopropanoate is a high-purity, specialized organic building block featuring a difluorinated aromatic ketone ester structure. This compound is a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients, valued for its precise molecular architecture. It is primarily required by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial precursor in the development of advanced herbicides and fungicides, leveraging the bioactivity of the difluorophenyl moiety.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, such as in cross-coupling reactions and carbonyl chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where applicable.

Basic Information

Product Name	Ethyl 3-(2,6-Difluorophenyl)-3-Oxopropanoate
CAS No.	97305-12-9
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	Ethyl 2,6-Difluorobenzoylacetate; Ethyl (2,6-Difluorobenzoyl)acetate; 3-Oxo-3-(2,6-difluorophenyl)propanoic acid ethyl ester; 2,6-Difluorobenzoylacetic Acid Ethyl Ester; Ethyl 3-Oxo-3-(2,6-difluorophenyl)propanoate; Acetic acid, (2,6-difluorobenzoyl)-, ethyl ester; DFBAE
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,6-Difluorophenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.