Description

(E)-Cefuroxime Axetil Discontinued is a specific isomeric form of a second-generation cephalosporin antibiotic prodrug. This product is offered for research and development purposes, including analytical reference standards and process development. It is primarily utilized by pharmaceutical R&D laboratories, quality control departments, and academic institutions engaged in antimicrobial research or method validation for related pharmaceutical compounds.

Application

• Pharmaceutical Reference Standard: Serves as a critical high-purity standard for analytical method development and validation in quality control laboratories.
• Research & Development: Used in preclinical studies to investigate the properties, stability, and degradation pathways of cefuroxime axetil isomers.
• Process Chemistry: Employed as an intermediate or a benchmark in the development and optimization of synthetic routes for cephalosporin antibiotics.
• Impurity Profiling: Essential for identifying and quantifying isomeric impurities in bulk active pharmaceutical ingredients (APIs) and finished dosage forms.
• Academic Research: Supports studies in medicinal chemistry, pharmacology, and antibiotic resistance mechanisms within university and institutional settings.

Basic Information

Product Name	(E)-Cefuroxime Axetil Discontinued
CAS No.	97232-96-7
Molecular Formula	C20H22N4O10S
Molecular Weight	510.48 g/mol
Synonyms	(E)-Cefuroxime Axetil; (E)-Cefuroxime 1-Acetoxyethyl Ester; (E)-Cefuroxime Acetoxyethyl Ester; (E)-Cefuroxime Pivaloyloxymethyl Ester (common misnomer); (6R,7R)-3-[(E)-Carbamoyloxymethyl]-7-[[(Z)-2-furan-2-yl-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Acetoxymethyl Ester; (E)-Isomer of Cefuroxime Axetil; Zinnat Isomer E
EINECS	Contact for details

Quality Control

Our (E)-Cefuroxime Axetil Discontinued is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including chromatographic purity assays and spectroscopic identification, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.