Description

L-Proline β-Naphthylamide Hydrochloride is a specialized biochemical derivative of the amino acid L-proline, coupled with a β-naphthylamide moiety. This compound serves as a critical chromogenic substrate for the detection and quantification of proline-specific peptidase and aminopeptidase activity in enzymatic assays. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors requiring precise enzyme characterization and inhibitor screening.

Application

• Chromogenic substrate for proline-specific endopeptidases and aminopeptidases in biochemical research.
• Key reagent in enzyme activity assays and kinetic studies for drug discovery and development.
• Used in the development and quality control of diagnostic kits for clinical analysis.
• Tool compound in microbiology for studying bacterial and fungal protease activity.
• Substrate for high-throughput screening (HTS) platforms to identify novel enzyme inhibitors.
• Reference standard in analytical method development and validation within QC laboratories.

Basic Information

Product Name	L-Proline β-Naphthylamide Hydrochloride
CAS No.	97216-16-5
Molecular Formula	C₁₅H₁₇N₃O•HCl
Molecular Weight	291.78 g/mol
Synonyms	L-Proline β-Naphthylamide HCl; Proline-2-Naphthylamide Hydrochloride; L-Pro-β-NA•HCl; N-(2-Naphthyl)-L-prolinamide Hydrochloride; L-Prolinamide, N-2-naphthalenyl-, hydrochloride (1:1); Proline β-Naphthylamide HCl; L-Proline-β-naphthylamide hydrochloride; Substrate for Proline Aminopeptidase
EINECS	Contact for details

Quality Control

Our L-Proline β-Naphthylamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and residual solvent analysis to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.