Description

2,2,2-Trifluoro-n-Piperidin-4-Yl-Acetamide is a high-purity trifluoromethylated piperidine derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the unique properties imparted by the trifluoroacetamide group, which is instrumental in modulating the pharmacokinetic and physicochemical profiles of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Chemical Biology Probe: Utilized as a molecular scaffold for developing biochemical probes and diagnostic agents.

Basic Information

Product Name	2,2,2-Trifluoro-n-Piperidin-4-Yl-Acetamide
CAS No.	97181-51-6
Molecular Formula	C7H11F3N2O
Molecular Weight	196.17 g/mol
Synonyms	4-(2,2,2-Trifluoroacetamido)piperidine; 2,2,2-Trifluoro-N-(piperidin-4-yl)acetamide; 1-(2,2,2-Trifluoroacetyl)piperidin-4-amine; 4-Amino-N-(2,2,2-trifluoroethyl)piperidine; 97181-51-6; TFAPA; Trifluoroacetamide piperidine derivative
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-Piperidin-4-Yl-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.