Description

E-Ceftizoxime Sodium Salt is a semi-synthetic, broad-spectrum third-generation cephalosporin antibiotic. Its primary value lies in its potent activity against a wide range of Gram-negative bacteria, including many β-lactamase-producing strains, making it a critical component in pharmaceutical research and development. This compound is essential for manufacturers and research institutions focused on developing sterile injectable antibiotic formulations and conducting microbiological studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of sterile injectable antibiotic drugs for clinical use.
• Microbiological Research: Used as a reference standard and active agent in antimicrobial susceptibility testing and mechanism of action studies.
• Hospital & Clinical Preparations: Serves as the key component for compounding injectable solutions in hospital pharmacy settings.
• Veterinary Medicine: Applied in the development of antibacterial treatments for veterinary applications.
• Analytical Standard: Employed as a high-purity standard for quality control (QC) and quality assurance (QA) testing in pharmaceutical laboratories.
• Biochemical Research: Utilized in studies exploring bacterial cell wall synthesis and inhibition pathways.

Basic Information

Product Name	E-Ceftizoxime Sodium Salt
CAS No.	97164-53-9
Molecular Formula	C13H12N5NaO5S2
Molecular Weight	405.38 g/mol
Synonyms	Ceftizoxime Sodium; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; FK-749; FR-13749; Ceftizox; Cefizox; Epocelin; Sodium (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylate
EINECS	Contact for details

Quality Control

Our E-Ceftizoxime Sodium Salt is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. A Certificate of Analysis (COA) documenting compliance with in-house specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	6.0 - 8.0
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile (upon request)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.