Description

(R)-(+)-4-Methoxymandelonitrile is a high-value chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its enantiopure nature makes it a critical precursor for the production of optically active pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral synthons for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry is crucial for biological activity and environmental safety.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D: A valuable compound for university and corporate research laboratories focused on organic synthesis, medicinal chemistry, and stereochemistry studies.

Basic Information

Product Name	(R)-(+)-4-Methoxymandelonitrile
CAS No.	97070-73-0
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(R)-4-Methoxymandelonitrile; (R)-(+)-p-Methoxymandelonitrile; (R)-α-Hydroxy-4-methoxybenzeneacetonitrile; (R)-2-Hydroxy-2-(4-methoxyphenyl)acetonitrile; (R)-(+)-4-Methoxybenzaldehyde cyanohydrin; (R)-4-Methoxy-α-hydroxybenzeneacetonitrile; (R)-O-Methylmandelonitrile (less common)
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-Methoxymandelonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination, to ensure it meets the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.