Description

1-(4-Fluoro-Phenyl)-Cyclopropanecarbonitrile is a versatile and high-value organic building block featuring a cyclopropane ring and a nitrile group on a fluorinated aromatic scaffold. This compound matters as a critical intermediate in modern synthetic chemistry, enabling the construction of complex molecules with precise stereochemistry and functional group compatibility. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential CNS agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers with tailored optical or electronic properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms and biological pathways due to its reactive nitrile handle.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring cyclopropane ring introduction.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-Cyclopropanecarbonitrile
CAS No.	97009-67-1
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	1-(4-Fluorophenyl)cyclopropanecarbonitrile; 4-(Cyanocyclopropyl)fluorobenzene; (4-Fluorophenyl)cyclopropanecarbonitrile; 1-(p-Fluorophenyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(4-fluorophenyl)-; 97009-67-1; p-Fluorophenyl cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-Phenyl)-Cyclopropanecarbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) for every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.