Description

Hemoglobin F-Pendergrass CAS NO 96957-57-2 is a specialized biochemical reference material, a fetal hemoglobin variant characterized by its Pendergrass mutation. This high-purity compound is critical for research and diagnostic applications requiring precise standards. It is primarily utilized by biotechnology firms, clinical research laboratories, and diagnostic kit manufacturers focused on hemoglobinopathies and hematological studies.

Application

• Biochemical Research Standard: Serves as a critical reference material for studies on fetal hemoglobin structure, function, and genetic mutations.
• Diagnostic Assay Development: Used as a calibrant and control in the development and validation of diagnostic tests for sickle cell disease and thalassemia.
• Clinical Laboratory Quality Control: Provides a known standard for internal quality assurance programs in clinical labs performing hemoglobin electrophoresis or HPLC analysis.
• Pharmaceutical Research: Employed in drug discovery and development projects targeting the modulation of fetal hemoglobin for therapeutic benefit.
• Academic & Institutional Research: Supports fundamental research in molecular biology, genetics, and protein chemistry related to hemoglobin variants.

Basic Information

Product Name	Hemoglobin F-Pendergrass
CAS No.	96957-57-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F-Pendergrass; Fetal Hemoglobin Pendergrass; Hemoglobin F (Pendergrass); HbF Pendergrass variant; γ-Globin variant Pendergrass; Fetal Hb Pendergrass; Pendergrass Hemoglobin F; Hemoglobin F Pendergrass Mutant
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Hemoglobin F-Pendergrass is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to a quality management system suitable for the production of research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or Certificate of Analysis. This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Lyophilized powder or specified form
Identification (IR / HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95% (or as specified per grade)
Protein Content	Determined by UV-Vis or other suitable method
Solubility	Specified buffer system
Moisture Content (KF)	< 5.0%
Biological Activity	As specified (e.g., oxygen binding)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.