Description

2-Amino-2-(2-Methoxyphenyl)Acetonitrile Hydrochloride is a high-purity, versatile chemical building block essential for advanced organic synthesis. Its primary value lies in its role as a key chiral intermediate for constructing complex pharmaceutical molecules, particularly those targeting the central nervous system. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and reference standards.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its unique aromatic amino nitrile structure.
• Fine Chemical Production: Serves as a specialized building block for creating complex molecules used in materials science and specialty chemistry.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Utilized in scale-up and route development for the commercial manufacturing of optically active compounds.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory submissions.

Basic Information

Item	Details
Product Name	2-Amino-2-(2-Methoxyphenyl)Acetonitrile Hydrochloride
CAS No.	96929-45-2
Molecular Formula	C10H13N2O•HCl
Molecular Weight	212.68 g/mol
Synonyms	2-Amino-2-(2-methoxyphenyl)acetonitrile hydrochloride; (2-Methoxyphenyl)glycinonitrile hydrochloride; α-Amino-o-methoxyphenylacetonitrile hydrochloride; 2-(2-Methoxyphenyl)-2-aminoacetonitrile hydrochloride; o-Methoxymandelonitrile amine hydrochloride; 96929-45-2; Glycine, 2-(2-methoxyphenyl)-, nitrile, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2-Methoxyphenyl)Acetonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.