Description

n-[(2-Propenyloxy)Carbonyl]-S-(Triphenylmethyl)-L-Cysteine is a sophisticated, protected amino acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in the synthesis of complex peptides and modified biomolecules, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Peptide Synthesis: A key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS), particularly for introducing cysteine residues with orthogonal protecting groups.
• Pharmaceutical Research: Used in the research and development of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Bioconjugation: Serves as a precursor for creating site-specifically modified proteins, antibody-drug conjugates (ADCs), and other bioconjugates.
• Chemical Biology: Employed in the study of protein function, structure-activity relationships (SAR), and the development of chemical probes.
• Material Science: Potential use in the synthesis of functionalized polymers and smart materials with peptide motifs.

Basic Information

Product Name	n-[(2-Propenyloxy)Carbonyl]-S-(Triphenylmethyl)-L-Cysteine
CAS No.	96865-72-4
Molecular Formula	C26H25NO4S
Molecular Weight	447.55 g/mol
Synonyms	N-Alloxycarbonyl-S-trityl-L-cysteine; Fmoc-Cys(Trt)-OH (Note: Common confusion, but this is the Alloc-protected analog); N-(Allyloxycarbonyl)-S-trityl-L-cysteine; L-Cysteine, N-[(2-propen-1-yloxy)carbonyl]-S-(triphenylmethyl)-; Alloc-Cys(Trt)-OH; N-Alloc-S-trityl-L-cysteine; Allyl N-[(S)-3-(triphenylmethylthio)-1-carboxypropyl]carbamate
EINECS	Contact for details

Quality Control

Our n-[(2-Propenyloxy)Carbonyl]-S-(Triphenylmethyl)-L-Cysteine is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range provided on COA
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.