Description

Bicyclo[2.2.2]Octane, 1-Ethynyl- (9Ci) is a specialized organic building block featuring a rigid bicyclic framework with a terminal alkyne functional group. This unique structure makes it a valuable intermediate for synthesizing complex molecules with precise three-dimensional geometry. It is primarily sought by researchers and process chemists in the pharmaceutical and advanced materials sectors for applications in drug discovery, ligand synthesis, and polymer cross-linking.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for creating conformationally restricted analogs.
• Click Chemistry Reagent: The terminal alkyne group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Ligand & Catalyst Development: Used to construct sophisticated, sterically defined ligands for asymmetric catalysis and organometallic complexes.
• Advanced Material Synthesis: Incorporated into monomers for high-performance polymers, dendrimers, and metal-organic frameworks (MOFs) to enhance thermal and mechanical properties.
• Academic & Industrial R&D: A critical tool in organic synthesis for constructing complex polycyclic and cage-like molecular architectures.

Basic Information

Product Name	Bicyclo[2.2.2]Octane, 1-Ethynyl- (9Ci)
CAS No.	96454-73-8
Molecular Formula	C10H12
Molecular Weight	132.20 g/mol
Synonyms	1-Ethynylbicyclo[2.2.2]octane; Ethynylbicyclo[2.2.2]octane; Bicyclo[2.2.2]oct-1-ylacetylene; 1-Bicyclo[2.2.2]octylethyne; (Bicyclo[2.2.2]oct-1-yl)acetylene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.