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3-(Boc-Amino)-3-(4-Methoxyphenyl)-1-Propanol CAS NO 96363-26-7


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CAS No.:96363-26-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(Boc-Amino)-3-(4-Methoxyphenyl)-1-Propanol is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine group by the Boc (tert-butoxycarbonyl) moiety, which allows for selective reactions and is readily cleaved under mild acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for constructing complex molecules like active pharmaceutical ingredients (APIs) and novel drug candidates.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
  • Peptidomimetics & Amino Acid Derivatives: Used to introduce the 3-(4-methoxyphenyl)-1-propanol side chain into peptide-like structures for drug discovery.
  • Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective reactions to create enantiomerically pure compounds.
  • Medicinal Chemistry Research: Utilized in the design and development of new chemical entities for biological screening and lead optimization.
  • Fine Chemical Production: Serves as a precursor for specialty chemicals, catalysts, and ligands used in various chemical processes.

Basic Information

Product Name 3-(Boc-Amino)-3-(4-Methoxyphenyl)-1-Propanol
CAS No. 96363-26-7
Molecular Formula C15H23NO4
Molecular Weight 281.35 g/mol
Synonyms 1-Propanol, 3-[(1,1-dimethylethoxy)carbonyl]amino-3-(4-methoxyphenyl)-; 3-[(tert-Butoxycarbonyl)amino]-3-(4-methoxyphenyl)-1-propanol; 3-(N-Boc-Amino)-3-(4-Methoxyphenyl)propan-1-ol; 3-(Boc-amino)-3-(p-methoxyphenyl)-1-propanol; Boc-4-MeO-Phe-ol; tert-Butyl [3-hydroxy-1-(4-methoxyphenyl)propyl]carbamate; N-Boc-3-amino-3-(4-methoxyphenyl)-1-propanol
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Quality Control

Our 3-(Boc-Amino)-3-(4-Methoxyphenyl)-1-Propanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and enantiomeric purity suitable for research and cGMP manufacturing. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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