Description

1-(Trifluoroethoxy)-2-Methyl-4-Nitrobenzene is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring a trifluoroethoxy group adjacent to a nitro substituent, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a specialized intermediate in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex aromatic systems via reactions such as nucleophilic aromatic substitution and catalytic cross-coupling.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized nitro- and fluoro-containing dyes and pigments for high-performance applications.

Basic Information

Product Name	1-(Trifluoroethoxy)-2-Methyl-4-Nitrobenzene
CAS No.	96308-26-8
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	2-Methyl-4-nitro-1-(2,2,2-trifluoroethoxy)benzene; 4-Nitro-2-methylphenyl trifluoroethyl ether; 1-Trifluoroethoxy-2-methyl-4-nitrobenzene; α,α,α-Trifluoro-2-methyl-4-nitrophenetole; 2-Methyl-1-(2,2,2-trifluoroethoxy)-4-nitrobenzene; 4-Nitro-α,α,α-trifluoro-o-cresol methyl ether
EINECS	Contact for details

Quality Control

Our 1-(Trifluoroethoxy)-2-Methyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and incompatible organic solvents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.