Description

Ioxabrolic Acid CAS NO 96191-65-0 is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its precise molecular structure is critical for developing high-performance, low-osmolality contrast agents used in diagnostic imaging. This high-purity intermediate is essential for manufacturers in the pharmaceutical and fine chemical sectors who require reliable, specification-grade raw materials for advanced synthesis. Consistent quality and supply chain integrity are paramount for its application in producing vital medical diagnostics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of non-ionic, iodinated X-ray contrast agents.
• Diagnostic Imaging: Used in the production of contrast media for enhanced visualization in computed tomography (CT) scans and angiography.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for novel diagnostic compounds.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring specific iodinated aromatic structures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) producing active pharmaceutical ingredients (APIs) for contrast media.

Basic Information

Product Name	Ioxabrolic Acid
CAS No.	96191-65-0
Molecular Formula	C17H14I3NO3
Molecular Weight	688.01 g/mol
Synonyms	5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid; Ioxabrolic Acid; Ioxabrol; ZK 35760; 5-(Acetylamino)-2,4,6-triiodo-N-methyl-1,3-benzenedicarboxamide; AD-210; NSC-351358
EINECS	Contact for details

Quality Control

Our Ioxabrolic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical intermediate use. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.