Description

Human Igf-Ii CAS NO 96081-16-2 is a high-purity recombinant protein, specifically the Insulin-like Growth Factor II, a critical signaling molecule involved in cell growth, proliferation, and differentiation. This product is essential for researchers and manufacturers requiring a reliable and consistent source of bioactive IGF-II for advanced life science applications. It is primarily utilized in pharmaceutical R&D, cell culture studies, and the development of therapeutic and diagnostic products targeting metabolic and growth disorders.

Application

• Cell Culture & Tissue Engineering: Used as a growth supplement in serum-free media to promote the proliferation of various mammalian cell lines.
• Biopharmaceutical Research: Serves as a key reagent in studying insulin-like growth factor signaling pathways, receptor interactions, and metabolic regulation.
• Therapeutic Development: Investigated as a potential active pharmaceutical ingredient (API) or critical raw material in formulations targeting growth deficiencies and metabolic diseases.
• Diagnostic Manufacturing: Employed as a standard or calibrator in immunoassay kits (e.g., ELISA) for the quantitative measurement of IGF-II levels in clinical samples.
• Biochemical Research: Utilized in protein-protein interaction studies, structural biology, and as a substrate for enzyme-linked assays.

Basic Information

Product Name	Human Igf-Ii
CAS No.	96081-16-2
Molecular Formula	C869H1383N253O255S7
Molecular Weight	~7471 Da (monoisotopic)
Synonyms	Insulin-like Growth Factor II; IGF-II; IGF-2; Somatomedin A; Multiplication-Stimulating Activity (MSA); IGF-II (1-67); Recombinant Human IGF-II; rhIGF-II; CAS 96081-16-2
EINECS	Contact for details

Quality Control

Our recombinant Human IGF-II is manufactured under stringent quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to a comprehensive battery of analytical tests, including identity confirmation by mass spectrometry, purity assessment by HPLC, and potency evaluation via cell-based bioassays. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting applications in GMP and GLP environments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Mass Spec)	Conforms to standard
Purity (HPLC)	≥ 95%
Molecular Weight	7471 ± 5 Da
Biological Activity (Cell Proliferation)	≥ 1 x 107 units/mg
Endotoxin	< 1.0 EU/µg
Solubility	Soluble in water or PBS (pH 7.2-7.4)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.