Description

S-(3-Nitrocarbobenzoxy)Glutathione is a specialized, chemically modified derivative of the essential antioxidant glutathione. This compound is a critical intermediate and research tool in the fields of biochemistry and pharmaceutical development, particularly for studying enzyme mechanisms and designing prodrugs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced synthesis and biochemical studies.

Application

• Biochemical Research: A key substrate and inhibitor for studying glutathione S-transferase (GST) enzymes and related metabolic pathways.
• Pharmaceutical Intermediate: Serves as a protected precursor in the synthesis of novel drug candidates targeting oxidative stress and detoxification processes.
• Proteomics & Cell Biology: Used as a tool compound to investigate redox signaling, protein S-glutathionylation, and cellular defense mechanisms.
• Enzyme Kinetics: Employed in enzymatic assays to determine kinetic parameters and inhibition constants for GST isoforms.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in related chemical and biological analyses.

Basic Information

Product Name	S-(3-Nitrocarbobenzoxy)Glutathione
CAS No.	95998-74-6
Molecular Formula	C19H25N5O10S
Molecular Weight	515.49 g/mol
Synonyms	S-(3-Nitrobenzyloxycarbonyl)glutathione; 3-Nitro-Z-GSH; Glutathione, S-[(3-nitrophenyl)methoxy]carbonyl]-; S-(3-Nitrobenzyloxycarbonyl)-L-glutathione; NSC 401005; S-Carbobenzoxy-3-nitroglutathione; S-(3-Nitro-Cbz)Glutathione; γ-Glu-Cys(3-NO2-Z)-Gly
EINECS	Contact for details

Quality Control

Our S-(3-Nitrocarbobenzoxy)Glutathione is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.