Description

7-Didemethyl Minocycline Dihydrochloride (>85% By Hplc) is a key semi-synthetic tetracycline derivative and a critical intermediate in advanced pharmaceutical synthesis. This high-purity compound is essential for researchers and manufacturers developing next-generation antibiotics and exploring novel therapeutic applications. It is primarily utilized in the pharmaceutical and biotechnology sectors for the research and development of new antimicrobial agents and as a reference standard in analytical chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel tetracycline-class antibiotics and other therapeutic compounds.
• Research & Development: Used in biochemical and pharmacological research to study antibiotic mechanisms of action, resistance, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and method development in HPLC and other chromatographic analyses.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new antibiotic formulations.
• Microbiological Studies: Utilized in in-vitro studies to assess efficacy against a broad spectrum of microorganisms.

Basic Information

Product Name	7-Didemethyl Minocycline Dihydrochloride (>85% By Hplc)
CAS No.	95940-02-6
Molecular Formula	C₂₂H₂₅N₃O₇ • 2HCl
Molecular Weight	544.37 g/mol (for free base C₂₂H₂₅N₃O₇)
Synonyms	7-Dedimethylminocycline Dihydrochloride; 7-Didesmethyl Minocycline 2HCl; Minocycline Impurity; 4,7-Bis(dedimethylamino)minocycline Dihydrochloride; 7-DDM Minocycline Dihydrochloride; Tetracycline Derivative Intermediate; 7-Desdimethylminocycline Dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 7-Didemethyl Minocycline Dihydrochloride is manufactured and tested under a strict quality management system. The primary assay is determined by HPLC to ensure a purity of >85%. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	> 85.0%
Water Content (KF)	< 5.0%
Residue on Ignition	< 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.