Description

Urotensin Ii CAS NO 95918-56-2 is a bioactive cyclic peptide hormone that plays a significant role in cardiovascular and renal physiology. This high-purity peptide is critical for advanced research and development in endocrinology and pharmacology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on cardiovascular disease, metabolic disorders, and novel therapeutic discovery.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating the urotensin system's role in blood pressure regulation and vascular tone.
• Drug Discovery & Development: Serves as a key biochemical tool for screening and validating potential drug candidates targeting the urotensin II receptor (UT receptor).
• Biochemical Assay Development: Employed in the development and calibration of immunoassays (ELISA, RIA) and receptor-binding assays to quantify urotensin-related activity.
• Academic & Clinical Studies: Facilitates fundamental research into its physiological and pathophysiological functions in heart failure, kidney disease, and metabolic syndrome.
• Peptide Chemistry Reference: Acts as a precise molecular standard for analytical method development using techniques like HPLC and mass spectrometry.

Basic Information

Product Name	Urotensin Ii
CAS No.	95918-56-2
Molecular Formula	C₁₀₆H₁₄₆N₂₈O₃₂S₂
Molecular Weight	2388.6 g/mol
Synonyms	Urotensin II; Human Urotensin II; hUII; U-II; Urotensin-2; UTS2; UII (1-11); Cyclo[L-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val]; H-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (disulfide bridge: Cys2-Cys7)
EINECS	Contact for details

Quality Control

Our Urotensin Ii is manufactured under strict quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.