Description

Iofetamine Hcl CAS NO 95896-48-3 is a high-purity chemical compound, specifically the hydrochloride salt of iofetamine, primarily utilized as a key intermediate in the synthesis of diagnostic radiopharmaceuticals. Its critical role lies in enabling the production of brain perfusion imaging agents, such as Iofetamine (123I), used in Single Photon Emission Computed Tomography (SPECT). This product is essential for pharmaceutical manufacturers, research institutions, and diagnostic imaging centers focused on neurology and cardiology. We ensure a reliable supply chain with stringent quality control to support advanced medical research and diagnostic applications globally.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the synthesis of the radiopharmaceutical Iofetamine (123I) for SPECT imaging.
• Neurological Diagnostics: Key component in agents used to assess cerebral blood flow and diagnose conditions like stroke, dementia, and epilepsy.
• Cardiac Imaging: Used in the development of radiopharmaceuticals for myocardial perfusion studies.
• Research & Development: Serves as a reference standard and building block in medicinal chemistry research for CNS-targeting compounds.
• Radiochemistry: Employed in laboratories specializing in the labeling of compounds with radioactive isotopes for diagnostic purposes.
• GMP Manufacturing: Supplied as a raw material for Good Manufacturing Practice (GMP) production of finished dosage forms in regulated environments.

Basic Information

Product Name	Iofetamine Hcl
CAS No.	95896-48-3
Molecular Formula	C12H18IN•HCl
Molecular Weight	339.64 g/mol
Synonyms	N-Isopropyl-4-iodoamphetamine hydrochloride; Iofetamine hydrochloride; HIPDM hydrochloride; 4-Iodo-N-isopropylamphetamine HCl; N-(3-Iodophenyl)-N-methyl-2-propylamine hydrochloride; (123I)Iofetamine precursor; IMP-HCl
EINECS	Contact for details

Quality Control

Our Iofetamine Hcl is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR. We provide full traceability and Certificates of Analysis (COA) that detail compliance with in-house specifications. The product is suitable for use in GMP environments, and custom purity grades, including USP/EP reference standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.