Description

n-(1-Oxo-2-Phenylbutyl)-L-Methionine is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a methionine-derived amino acid backbone and a phenylbutyl ketone moiety, making it a versatile precursor for complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptide mimetics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptidomimetic Research: Serves as a constrained amino acid analog for constructing peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Used in the synthesis of labeled compounds or affinity probes for studying enzyme mechanisms and protein interactions.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce chiral centers.
• Academic & Industrial R&D: Utilized in exploratory chemistry for novel compound libraries and material science applications.

Basic Information

Product Name	n-(1-Oxo-2-Phenylbutyl)-L-Methionine
CAS No.	95873-64-6
Molecular Formula	C₁₅H₂₁NO₃S
Molecular Weight	295.40 g/mol
Synonyms	L-Methionine, N-(1-oxo-2-phenylbutyl)-; (2S)-2-[(1-Oxo-2-phenylbutyl)amino]-4-(methylsulfanyl)butanoic acid; N-(2-Phenylbutyryl)-L-methionine; 2-Phenylbutyryl-L-methionine; 95873-64-6; L-Methionine N-(2-phenylbutyryl)-; N-(1-Oxo-2-phenylbutyl)methionine
EINECS	Contact for details

Quality Control

Our n-(1-Oxo-2-Phenylbutyl)-L-Methionine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.