Description

Atrial Natriuretic Factor 88 is a synthetic peptide fragment corresponding to a specific sequence of the atrial natriuretic peptide (ANP) hormone. This compound is a critical research tool for studying cardiovascular physiology, renal function, and the mechanisms of blood pressure regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on cardiometabolic diseases and novel therapeutic pathways.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the ANP receptor pathway, natriuresis, and vasodilation.
• Pharmaceutical Development: Serves as a key intermediate or pharmacological tool in the discovery and screening of drugs targeting hypertension, heart failure, and renal disorders.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to measure ANP levels in biological samples.
• Signal Transduction Studies: Applied in cellular and molecular biology research to elucidate downstream signaling cascades activated by natriuretic peptide receptors.
• Biochemical Reagent: Functions as a high-purity biochemical for enzymatic studies, protein interaction analyses, and structural biology.

Basic Information

Product Name	Atrial Natriuretic Factor 88
CAS No.	95828-41-4
Molecular Formula	C106H172N36O33S2
Molecular Weight	2447.8 g/mol
Synonyms	ANF (88-115), Atrial Natriuretic Peptide (88-115), ANP (88-115), Cardionatrin (88-115), Atriopeptin (88-115), rANP (88-115), Auriculin A (88-115), H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys105-Cys121)
EINECS	Contact for details

Quality Control

Every batch of Atrial Natriuretic Factor 88 is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous testing, including advanced chromatographic and spectroscopic methods, to meet the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, HPLC profile, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.