Description

Br-Aam-Pindolol CAS NO 95778-69-1 is a specialized brominated derivative of the β-blocker Pindolol, designed for advanced pharmaceutical research and development. This high-purity intermediate is critical for medicinal chemists exploring novel drug candidates and studying structure-activity relationships (SAR). It is primarily utilized by R&D laboratories and pharmaceutical companies engaged in the synthesis of new chemical entities (NCEs) for cardiovascular and neurological applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel β-adrenergic receptor ligands and analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modify the pharmacological profile of Pindolol derivatives.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and early-stage development of new cardiovascular or neurological drug candidates.
• Biochemical Tool Compound: Acts as a labeled or modified probe for studying β-adrenergic receptor interactions in biochemical assays.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Br-Aam-Pindolol
CAS No.	95778-69-1
Molecular Formula	C₁₄H₂₀BrN₃O₂
Molecular Weight	342.23 g/mol
Synonyms	1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, Bromoacetamido-Pindolol; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1H-indole-7-carboxamide, Bromo Derivative; Pindolol Bromoacetamide; Br-AAM-Pindolol; N-(4-[2-Hydroxy-3-(isopropylamino)propoxy]-1H-indol-7-yl)-2-bromoacetamide
EINECS	Contact for details

Quality Control

Our Br-Aam-Pindolol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.