Description

Cefotiam Hexetil Hydrochloride is a prodrug ester of the second-generation cephalosporin antibiotic, Cefotiam, designed to enhance oral bioavailability. This compound is critical for the development and production of effective oral antibacterial formulations targeting a broad spectrum of gram-positive and gram-negative bacteria. It is primarily required by pharmaceutical manufacturers and research institutions engaged in antibiotic development, clinical studies, and generic drug production.

Application

• Active Pharmaceutical Ingredient (API) for oral antibiotic formulations.
• Pharmaceutical Intermediates in the synthesis of finished dosage forms like tablets and capsules.
• Research & Development of new antibacterial therapies and combination drugs.
• Reference Standard for quality control and analytical testing in laboratories.
• Generic Drug Manufacturing for cost-effective antibiotic production.
• Veterinary Medicine applications in treating bacterial infections in animals.

Basic Information

Product Name	Cefotiam Hexetil Hydrochloride
CAS No.	95761-91-4
Molecular Formula	C27H34N6O7S2·HCl
Molecular Weight	663.18 g/mol (for free base)
Synonyms	Cefotiam Hexetil HCl; Cefotiam Hexyldihydrogenphosphate Ester Hydrochloride; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[1-[2-(diethylamino)ethyl]-1H-tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hexyl Ester Hydrochloride; HR-580; T-2588; Cefotiam Hexetil Monohydrochloride
EINECS	Contact for details

Quality Control

Our Cefotiam Hexetil Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.