Description

5-Fluoro-2-Methylanisole is a versatile fluorinated aromatic ether building block of significant importance in advanced organic synthesis. Its value lies in the strategic combination of fluorine and methoxy substituents, which are crucial for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the 2-methyl-5-fluoroanisole moiety into complex molecules.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized fluorinated dyes and pigments that offer enhanced light fastness and unique color properties.

Basic Information

Item	Detail
Product Name	5-Fluoro-2-Methylanisole
CAS No.	95729-22-9
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	1-Fluoro-4-methoxy-2-methylbenzene; 2-Methyl-5-fluoroanisole; 5-Fluoro-o-cresol methyl ether; 4-Fluoro-2-methoxytoluene; 2-Methoxy-5-fluorotoluene; 5-Fluoro-2-methoxytoluene; 5-Fluoro-2-methylphenyl methyl ether
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylanisole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.