Description

3-(Bromoacetyl)Chloramphenicol is a chemically modified derivative of the classic antibiotic chloramphenicol, where a bromoacetyl group has been introduced. This modification is crucial for creating targeted prodrugs and advanced intermediates used in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life sciences industries for synthesizing novel antimicrobial agents and for biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel chloramphenicol prodrugs and analogs with potentially improved pharmacological profiles.
• Antibiotic Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of antibiotic action.
• Medicinal Chemistry: Serves as a versatile precursor for introducing the bromoacetyl moiety into complex molecules for targeted drug delivery systems.
• Bioconjugation: The reactive bromoacetyl group enables its use in conjugating chloramphenicol derivatives to carriers, antibodies, or other biomolecules for research purposes.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-(Bromoacetyl)Chloramphenicol
CAS No.	95610-68-7
Molecular Formula	C13H15Br2Cl2N2O6
Molecular Weight	511.98 g/mol
Synonyms	Chloramphenicol 3-(bromoacetate); 2,2-Dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide 3-(bromoacetate); 3-O-(Bromoacetyl)chloramphenicol; Bromoacetyl chloramphenicol; 1-(4-Nitrophenyl)-2-(dichloroacetamido)-1,3-propanediol 3-bromoacetate
EINECS	Contact for details

Quality Control

Our 3-(Bromoacetyl)Chloramphenicol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.