Description

Procainamide 4-Hydroxylamine is a key chemical intermediate and reference standard of significant importance in pharmaceutical research and development. This compound is critical for the synthesis and analytical characterization of procainamide and its metabolites, which are central to cardiovascular therapeutics. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug development, quality control, and metabolic studies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Procainamide and related antiarrhythmic drug compounds.
• Analytical Reference Standard: Used as a certified standard in High-Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), and other analytical methods for drug quantification and impurity profiling.
• Metabolite Research: Essential for studying the metabolic pathways, pharmacokinetics, and pharmacodynamics of Procainamide in biological systems.
• Quality Control & Assurance: Employed in pharmaceutical quality control laboratories to validate analytical methods and ensure batch-to-batch consistency of active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in enzymatic and receptor-binding studies to investigate drug mechanisms of action.
• Impurity Standard: Serves as a characterized impurity standard for compliance with ICH guidelines on pharmaceutical impurities (Q3A & Q3B).

Basic Information

Product Name	Procainamide 4-Hydroxylamine
CAS No.	95576-27-5
Molecular Formula	C13H21N3O2
Molecular Weight	251.33 g/mol
Synonyms	4-Hydroxyamino-N-(2-diethylaminoethyl)benzamide; Procainamide Hydroxylamine; N-(2-Diethylaminoethyl)-4-hydroxyaminobenzamide; 4'-Hydroxyaminoprocainamide; Procainamide N-Oxide (related); PCAHA; Procainamide metabolite standard.
EINECS	Contact for details

Quality Control

Our Procainamide 4-Hydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS to ensure it meets high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.