Description

Tyrosyl-Threonyl-Glycyl-(4-Azidophenylalanyl)-Leucyl-Threonine is a specialized synthetic peptide sequence containing a photoreactive azido group, making it a critical tool for advanced biochemical research and development. This compound is engineered for applications requiring precise photoaffinity labeling and cross-linking studies to investigate protein-protein interactions and receptor binding sites. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on proteomics, drug discovery, and molecular biology.

Application

• Photoaffinity Labeling Probe: Used to covalently tag and identify biological targets, such as enzymes and receptors, upon UV light activation.
• Bioconjugation & Cross-linking Agent: Facilitates the study of protein-protein interactions and the construction of biomolecular complexes.
• Peptide-based Drug Discovery: Serves as a key intermediate or active component in the development of novel therapeutic peptides.
• Proteomics Research: Employed in mass spectrometry-based workflows for mapping binding sites and structural analysis.
• Biochemical Assay Development: Utilized in creating diagnostic assays and screening platforms that require specific, irreversible binding.
• Material Science & Biomaterials: Applied in surface functionalization and the development of bioactive coatings for medical devices.

Basic Information

Product Name	Tyrosyl-Threonyl-Glycyl-(4-Azidophenylalanyl)-Leucyl-Threonine
CAS No.	95537-15-8
Molecular Formula	C38H52N10O12
Molecular Weight	840.89 g/mol
Synonyms	YTG(pAzF)LT; Tyr-Thr-Gly-(4-Azido-Phe)-Leu-Thr; H-Tyr-Thr-Gly-(4-Azido-Phe)-Leu-Thr-OH; Photoactivatable YTGFLT Peptide; Azido-phenylalanine-containing Hexapeptide; p-Azido-L-phenylalanine Peptide Derivative; N-(4-Azidobenzoyl) Peptide Intermediate; Azidophenylalanine-modified Bio-conjugation Linker
EINECS	Contact for details

Quality Control

Our Tyrosyl-Threonyl-Glycyl-(4-Azidophenylalanyl)-Leucyl-Threonine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for peptide synthesis, and custom purity grades, including research-grade and GMP-grade materials, are available upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, temperature-controlled environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions, moisture, or light will compromise stability and activity. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.