Description

(R)-(+)-4-Isopropyl-2-Oxazolidinone is a high-value, enantiomerically pure chiral auxiliary and building block. This compound is essential for the stereoselective synthesis of complex organic molecules, enabling the production of single-isomer pharmaceuticals and fine chemicals. It is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and specialty compounds.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Widely used to induce stereoselectivity in aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: Key building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• Catalyst and Ligand Precursor: Serves as a starting material for synthesizing novel chiral catalysts and ligands for transition metal catalysis.
• Academic and Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Used in the manufacture of specialty flavors, fragrances, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(R)-(+)-4-Isopropyl-2-Oxazolidinone
CAS No.	95530-58-8
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(R)-4-Isopropyl-2-oxazolidinone; (R)-(+)-4-(1-Methylethyl)-2-oxazolidinone; (R)-4-Isopropyloxazolidin-2-one; (R)-Boc-4-isopropyl-2-oxazolidinone (derivative); (R)-N-Boc-4-isopropyl-2-oxazolidinone (derivative); (R)-Evans Auxiliary derivative; (R)-4-iPr-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-Isopropyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for asymmetric synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.