Description

Angiotensin I, Sar(1)-Val(5)-n-Me-Ala(7)- is a synthetic, modified peptide analog of the endogenous hormone Angiotensin I, designed for enhanced stability and specific biological activity. This compound is a critical research tool for studying the renin-angiotensin system (RAS), a key regulator of blood pressure and fluid balance. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and academic institutions engaged in cardiovascular research, drug discovery, and biochemical assay development.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies of angiotensin-converting enzyme (ACE) and other proteases within the RAS pathway.
• Drug Discovery & Screening: Serves as a key ligand in high-throughput screening (HTS) assays to identify and characterize novel ACE inhibitors and receptor modulators.
• Pharmacological Studies: Employed in in vitro and ex vivo models to investigate the physiological effects and signaling mechanisms of angiotensin peptides.
• Antibody & Assay Development: Acts as an antigen for the production of specific antibodies or as a calibrator in immunoassays (e.g., ELISA) for angiotensin peptide quantification.
• Metabolic Pathway Analysis: Facilitates research into peptide metabolism and the generation of active angiotensin fragments.

Basic Information

Product Name	Angiotensin I, Sar(1)-Val(5)-n-Me-Ala(7)-
CAS No.	95262-82-1
Molecular Formula	C49H71N13O12
Molecular Weight	1010.2 g/mol
Synonyms	Sar(1)-Val(5)-N-Me-Ala(7)-Angiotensin I; [Sar1, Val5, N-Me-Ala7]-Angiotensin I; N-Methylalanine7-Angiotensin I (1-10) decapeptide; Modified Angiotensin I; Angiotensin I analog; Asp-Arg-Val-Tyr-Ile-His-Pro-N-Me-Ala-Phe
EINECS	Contact for details

Quality Control

Our Angiotensin I, Sar(1)-Val(5)-n-Me-Ala(7)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.