Description

(n-Cbz-Methylamino)Acetonitrile is a protected amino acetonitrile derivative, serving as a versatile and high-purity building block in advanced organic synthesis. Its core value lies in enabling the controlled introduction of the methylamino acetonitrile moiety, a key intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors and other small molecule therapeutics.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics, where the Cbz-protected amine and nitrile functionality allow for further selective chemical transformations.
• Agrochemical Research: Serves as a key precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitrile group.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(n-Cbz-Methylamino)Acetonitrile
CAS No.	95215-90-0
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-N-methylglycinonitrile; N-Carbobenzyloxy-N-methylaminoacetonitrile; (N-Cbz-N-methylamino)acetonitrile; (N-Cbz-Methylamino)Acetonitrile; N-Cbz-N-methylglycinonitrile; N-Methyl-N-[(phenylmethoxy)carbonyl]glycinonitrile; Z-N-methyl-aminoacetonitrile; Benzyl N-(cyanomethyl)-N-methylcarbamate
EINECS	Contact for details

Quality Control

Our (n-Cbz-Methylamino)Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality assurance supports your critical synthesis work with reliable and traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.