Description

Angiotensin I, Asn(1)-Val(5)-Gly(9)- is a specific, modified peptide fragment of the renin-angiotensin system hormone, Angiotensin I. This compound is of significant value in biochemical and pharmaceutical research for studying enzyme kinetics, receptor binding, and metabolic pathways related to blood pressure regulation. It is primarily required by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in cardiovascular drug discovery and development.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic assays, particularly for studies involving Angiotensin-Converting Enzyme (ACE) and other proteases.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the research and development of novel antihypertensive drugs and cardiovascular therapies.
• Diagnostic Reagents: Employed in the production of calibration standards and controls for clinical diagnostic tests measuring components of the renin-angiotensin system.
• Peptide Chemistry Studies: Utilized as a model compound in peptide synthesis optimization, stability testing, and structure-activity relationship (SAR) studies.
• Cell Signaling & Physiology: Applied in in vitro and ex vivo experiments to investigate cellular signaling pathways related to vasoconstriction and aldosterone secretion.

Basic Information

Product Name	Angiotensin I, Asn(1)-Val(5)-Gly(9)-
CAS No.	95211-04-4
Molecular Formula	C62H89N17O14
Molecular Weight	1288.5 g/mol
Synonyms	Angiotensin I (5-10) fragment; [Asn1, Val5, Gly9]-Angiotensin I; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu (modified); H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH (sequence variant); DRVYIHPFHL (modified); Ang I (1-10) fragment analog; Angiotensin I peptide analog
EINECS	Contact for details

Quality Control

Our Angiotensin I, Asn(1)-Val(5)-Gly(9)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.