Description

n-Methoxy-n-Methyl-2-Phenylacetamide is a versatile and high-value chemical intermediate, primarily recognized as a Weinreb amide derivative. This compound is critical for facilitating controlled carbonyl transformations in complex organic syntheses. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for ketone and aldehyde formation via Grignard or organolithium reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require precise molecular architecture.
• Organic Synthesis Reagent: Serves as a protected glycine equivalent or a masked acetyl synthon in multi-step laboratory and pilot-scale syntheses.
• Peptidomimetics Research: Employed in the development of novel peptide analogs and protease inhibitors for drug discovery programs.
• Material Science: Acts as a building block for specialty polymers and liquid crystals that require specific aromatic amide functionalities.
• Academic & R&D: A valuable reagent for methodological development in university and industrial research laboratories focusing on new synthetic methodologies.

Basic Information

Product Name	n-Methoxy-n-Methyl-2-Phenylacetamide
CAS No.	95092-10-7
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	N-Methoxy-N-methyl-2-phenylacetamide; 2-Phenyl-N-methoxy-N-methylacetamide; Weinreb Amide of Phenylacetic Acid; N-Methoxy-N-methylphenylacetamide; Phenylacetic acid N-methoxy-N-methylamide; N-Methoxy-N-methyl-α-toluamide; N,2-Dimethoxy-N-methyl-2-phenylethanamide; N-Methyl-N-methoxyphenylacetamide
EINECS	Contact for details

Quality Control

Every batch of n-Methoxy-n-Methyl-2-Phenylacetamide is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.