Description

Tumor Necrosis Factor Precursor is a critical protein involved in the regulation of immune cell signaling and inflammatory responses. This compound serves as a vital research tool for studying the mechanisms of cytokine biology, autoimmune diseases, and cancer immunology. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on developing novel therapeutic agents and diagnostic assays.

Application

• Biopharmaceutical Research & Development: Used as a key reference standard and starting material in the development of TNF-targeting therapies, including monoclonal antibodies and fusion proteins.
• Immunology & Cell Signaling Studies: Essential for in vitro and in vivo research to understand the TNF-mediated pathways in inflammation, apoptosis, and cell proliferation.
• Diagnostic Assay Development: Serves as a critical antigen and calibrator in the development of immunoassays (e.g., ELISA) for detecting TNF-related biomarkers in clinical samples.
• Drug Discovery Screening: Utilized in high-throughput screening platforms to identify and validate new small-molecule or biologic inhibitors of TNF activity.
• Academic & Contract Research: A fundamental reagent for universities and CROs conducting basic and applied research in cytokine biology and related disease models.
• Quality Control & Process Development: Employed as a standard in the QC testing of biologics and in the optimization of upstream/downstream biomanufacturing processes.

Basic Information

Product Name	Tumor Necrosis Factor Precursor
CAS No.	94948-60-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TNF Precursor; Tumor Necrosis Factor-alpha Precursor; TNF-α Precursor; Cachectin Precursor; TNF Superfamily Member 2 Precursor; TNFA Precursor; TNF A Precursor; Transmembrane TNF-alpha
EINECS	Contact for details

Quality Control

Our Tumor Necrosis Factor Precursor is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity. We adhere to relevant guidelines for research-grade biologics to support your critical R&D and process development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot as received to maintain optimal activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Contact for details
Moisture Content (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.