Description

6-((n-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl)Amino)-Hexanoyl)Sphingosyl Phosphocholine is a high-purity, fluorescently labeled sphingolipid derivative, specifically designed for advanced research applications. Its core value lies in enabling the precise tracking and visualization of sphingolipid metabolism, localization, and trafficking within cellular systems. This compound is essential for researchers in lipidomics, cell biology, and fluorescence microscopy who require reliable, well-characterized probes for critical studies.

Application

• Fluorescent Cell Labeling: Used as a vital fluorescent probe for labeling cellular membranes and tracking sphingolipid dynamics in live or fixed cells.
• Lipid Raft and Membrane Microdomain Studies: Essential for investigating the role of sphingolipids in the formation and function of lipid rafts and other membrane domains.
• Intracellular Trafficking Research: Enables visualization and analysis of the intracellular transport pathways of sphingomyelin and related metabolites.
• Biochemical Assay Development: Serves as a key substrate or standard in developing enzymatic assays for sphingolipid-metabolizing enzymes like sphingomyelinases.
• Apoptosis and Cell Signaling Studies: Applied in research focused on understanding the signaling roles of ceramide and sphingosine-1-phosphate pathways.
• Model Membrane Systems: Incorporated into liposomes or supported lipid bilayers to create fluorescently tagged model systems for biophysical studies.

Basic Information

Product Name	6-((n-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl)Amino)-Hexanoyl)Sphingosyl Phosphocholine
CAS No.	94885-04-8
Molecular Formula	C41H74N5O9P
Molecular Weight	812.03 g/mol
Synonyms	NBD C6-Sphingosyl Phosphocholine; NBD-C6-Sphingosylphosphocholine; NBD-C6-Sphingosylphosphocholine; 6-((N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosylphosphocholine; Fluorescent Sphingomyelin Analog; NBD-labeled Sphingomyelin; NBD-SM; NBD-Sphingomyelin (C6)
EINECS	Contact for details

Quality Control

Our 6-((n-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl)Amino)-Hexanoyl)Sphingosyl Phosphocholine is manufactured under strict quality protocols to ensure the high purity and batch-to-batch consistency required for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence characteristics. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and mass spectrometry, are validated to provide reliable data for your research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.