Description

1,2-(Palmitoyl-Nbd-Aminocaproyl)Phosphatidylethanolamine is a specialized, fluorescently labeled phospholipid derivative, designed for advanced research and diagnostic applications. Its core value lies in the covalent attachment of the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore, which provides a powerful tool for real-time visualization and tracking of lipid dynamics in complex biological systems. This high-purity compound is essential for researchers and developers in the fields of membrane biophysics, lipidomics, cell biology, and the development of lipid-based drug delivery systems such as liposomes.

Application

• Membrane Biophysics Research: As a fluorescent probe to study lipid bilayer properties, phase transitions, and membrane fluidity.
• Lipid Trafficking & Metabolism Studies: To visualize and quantify the intracellular transport, sorting, and metabolic fate of phosphatidylethanolamine.
• Liposome & Nanoparticle Development: As a traceable component in the formulation of fluorescently tagged liposomes for drug delivery research and biodistribution studies.
• Cell Biology Assays: For labeling cellular membranes, investigating membrane fusion/fission events, and studying apoptosis.
• Diagnostic Kit Development: As a key reagent in fluorescence-based assays and sensors for enzymatic activity (e.g., phospholipases) or lipid-protein interactions.
• Model Membrane Systems: Incorporation into supported lipid bilayers (SLBs) or giant unilamellar vesicles (GUVs) for in vitro studies.

Basic Information

Product Name	1,2-(Palmitoyl-Nbd-Aminocaproyl)Phosphatidylethanolamine
CAS No.	108762-10-3
Molecular Formula	C52H88N5O12P
Molecular Weight	1006.25 g/mol
Synonyms	NBD-PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine; DPPE-NBD; Fluorescent DPPE; NBD labeled phosphatidylethanolamine; NBD Phosphatidylethanolamine; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(NBD)
EINECS	Contact for details

Quality Control

Our 1,2-(Palmitoyl-Nbd-Aminocaproyl)Phosphatidylethanolamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, and spectroscopic analysis for fluorophore integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, methanol, DMSO
Fluorescence Properties	Excitation ~460 nm, Emission ~534 nm (in methanol)
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.