Description

Omega(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)-D-Erythro-Sphingosine-1-Phosphocholine CAS NO 1246303-02-5 is a high-purity, fluorescently labeled sphingolipid derivative, specifically a ceramide-1-phosphate analog, designed for advanced biochemical research. This compound is critical for studying sphingolipid metabolism, cell signaling pathways, and membrane dynamics with high sensitivity due to its NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) fluorophore. It is an essential tool for researchers and pharmaceutical developers in life sciences, particularly in lipidomics, cell biology, and the development of targeted therapies.

Application

• Biochemical Research & Lipidomics: Used as a fluorescent tracer to study the metabolism, trafficking, and intracellular localization of sphingolipids and ceramide-1-phosphate.
• Cell Signaling Studies: Investigates the role of sphingolipid-derived signaling molecules in processes like apoptosis, proliferation, and inflammation.
• Membrane Biophysics: Serves as a probe for analyzing lipid bilayer properties, membrane fluidity, and lipid-protein interactions.
• Drug Discovery & Development: Employed in high-throughput screening assays to identify modulators of sphingolipid-metabolizing enzymes like ceramide kinase.
• Diagnostic Assay Development: Acts as a key component in developing fluorescent-based diagnostic kits for enzymatic activity related to lipid pathways.
• Academic & Pharmaceutical R&D: Essential for fundamental research in universities and for target validation in biopharmaceutical companies.

Basic Information

Product Name	Omega(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)-D-Erythro-Sphingosine-1-Phosphocholine
CAS No.	1246303-02-5
Molecular Formula	C₃₄H₆₀N₅O₁₀P
Molecular Weight	717.85 g/mol
Synonyms	NBD C1P; NBD-Ceramide-1-Phosphate; NBD-C1P; 1-O-[6-[[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine-1-phosphocholine; Fluorescent Ceramide-1-Phosphate; NBD-labeled Sphingosine Phosphocholine; NBD-D-erythro-C1P; NBD-Cer-1-P
EINECS	Contact for details

Quality Control

Our Omega(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)-D-Erythro-Sphingosine-1-Phosphocholine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.