Description

Polysucrose is a high-molecular-weight, synthetic polymer derived from sucrose, widely recognized for its utility as a density gradient medium in biological separations. Its core value proposition lies in its ability to form inert, iso-osmotic, and non-ionic solutions ideal for the gentle and efficient isolation of cells, organelles, and viruses. This product is essential for research and development laboratories, diagnostic kit manufacturers, and biopharmaceutical companies engaged in cell biology, immunology, and virology. Its consistent performance and high purity make it a critical reagent for ensuring reproducible results in sensitive analytical and preparative techniques.

Application

• Density gradient centrifugation for the isolation of lymphocytes, platelets, and other blood cells.
• Purification of subcellular organelles, including mitochondria, nuclei, and peroxisomes.
• Virus purification and concentration in vaccine development and virology research.
• Separation of lipoproteins in clinical chemistry and metabolic studies.
• As a cushion or barrier layer in cell culture and sample preparation workflows.
• Component in diagnostic assay reagents requiring a stable, inert medium.
• Research applications in marine biology for separating plankton and other particulates.
• Preparative steps in proteomics and genomics for sample cleanup and fractionation.

Basic Information

Product Name	Polysucrose
CAS No.	26873-85-8
Molecular Formula	(C12H20O10)n
Molecular Weight	High polymer (Typically 400,000 - 700,000 Da)
Synonyms	Poly(sucrose); Sucrose polymer; Ficoll® (common trade name); Polysucrose 400; Polysucrose 70; Polyfructosan S; Density gradient medium; Colloidal polysucrose
EINECS	Contact for details

Quality Control

Our Polysucrose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including assessment of molecular weight distribution, osmolarity, pH, and endotoxin levels, to meet the stringent requirements of life science research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant pharmacopeial standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption, which can affect physical properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (on dried basis)	≥ 95.0%
Loss on Drying	≤ 5.0%
pH (in solution)	5.0 - 7.0
Osmolality	Contact for details
Endotoxin	< 0.1 EU/mg (for specific grades)
Molecular Weight (Avg.)	Specified grade (e.g., 400,000 Da)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.