Description

19,20-Epoxycytochalasin D is a potent and highly specific derivative of the cytochalasin family, known for its unique ability to inhibit actin polymerization. This compound is a critical research tool for studying cytoskeletal dynamics, cell motility, and morphology in biological systems. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in cell biology, cancer research, and drug discovery programs.

Application

• Cytoskeleton Research: A fundamental tool for investigating actin filament dynamics, cell shape, and intracellular transport mechanisms.
• Cell Biology Studies: Used to probe the role of the actin cytoskeleton in processes such as cell division, migration, and adhesion.
• Cancer Research: Employed in studies exploring tumor cell invasion, metastasis, and the development of anti-metastatic therapeutic agents.
• Neuroscience: Applied in research on neuronal growth cone guidance, synaptic plasticity, and the structural dynamics of dendritic spines.
• Drug Discovery Screening: Serves as a reference compound or positive control in high-throughput screens for molecules targeting the actin cytoskeleton.
• Microbiology: Used to study host-pathogen interactions, particularly how intracellular pathogens manipulate the host cell's actin network.

Basic Information

Product Name	19,20-Epoxycytochalasin D
CAS No.	191349-10-7
Molecular Formula	C30H39NO6
Molecular Weight	509.64 g/mol
Synonyms	19,20-Epoxycytochalasin D; Cytochalasin D, 19,20-epoxy-; (1S,2Z,4E,6S,7S,8E,11S,12E,14S,15R,16S,18S)-15-(Benzyloxy)-4,8,12,16-tetramethyl-11-[(1S)-1-methylpropyl]-17-oxa-13-azabicyclo[14.2.1]nonadeca-2,4,8,12-tetraene-7,18-dione; Epoxycytochalasin D
EINECS	Contact for details

Quality Control

Our 19,20-Epoxycytochalasin D is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, keep desiccated at -80°C. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.